MBP (85-99) peptide antagonist

• 产品号: M0571
• CAS号: 444305-16-2(freebase)
• 分子式: C72H115F3N18O23
• 分子量: 1657.7855096
• 纯 度: 95% (HPLC)

产品别名

• 标题: MBP (85-99) peptide antagonist trifluoroacetate salt
• IUPAC标准名: (4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-5-amino-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(2S)-1-[(2S)-2-{[(1S)-1-carboxyethyl]carbamoyl}pyrrolidin-1-yl]-1-oxopropan-2-yl]carbamoyl}ethyl]carbamoyl}ethyl]carbamoyl}ethyl]carbamoyl}pentyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]carbamoyl}ethyl]carbamoyl}-4-[(2S)-2-[(2S)-6-amino-2-{[(2S)-1-[(2S)-6-amino-2-[(2S)-2-amino-4-carboxybutanamido]hexanoyl]pyrrolidin-2-yl]formamido}hexanamido]-3-methylbutanamido]butanoic acid; trifluoroacetic acid
• IUPAC传统名: (4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-5-amino-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(2S)-1-[(2S)-2-{[(1S)-1-carboxyethyl]carbamoyl}pyrrolidin-1-yl]-1-oxopropan-2-yl]carbamoyl}ethyl]carbamoyl}ethyl]carbamoyl}ethyl]carbamoyl}pentyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]carbamoyl}ethyl]carbamoyl}-4-[(2S)-2-[(2S)-6-amino-2-{[(2S)-1-[(2S)-6-amino-2-[(2S)-2-amino-4-carboxybutanamido]hexanoyl]pyrrolidin-2-yl]formamido}hexanamido]-3-methylbutanamido]butanoic acid; trifluoroacetic acid

产品登记号

• CAS号: 444305-16-2(freebase)

产品性质

• 主要成分: Peptide content, 63% HPLC
• Empirical Formula (Hill Notation): C70H114N18O21 · xC2HF3O2
• 纯度: 95% (HPLC)
• 运输包装: dry ice
• 外观: lyophilized powder
• 溶解度: H2O: >1 mg/mL
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Amino Acid Sequence
Glu-Lys-Pro-Lys-Val-Glu-Ala-Tyr-Lys-Ala- Ala- Ala- Ala-Pro-Ala
Biochem/physiol Actions
MBP (85-99) peptide antagonist inhibits the binding of MBP 85-99 to HLA-DR2 and IL-2 and is a tool for MS research. The peptide antagonist is a 15-mer peptide that competes with Myelin Basic Protein MBP (85-99), the immunodominant epitope of MBP and major candidate autoantigen in multiple sclerosis (MS).

详细说明 (简体中文)

Amino Acid Sequence
Glu-Lys-Pro-Lys-Val-Glu-Ala-Tyr-Lys-Ala- Ala- Ala- Ala-Pro-Ala
Biochem/physiol Actions
MBP (85-99) peptide antagonist inhibits the binding of MBP 85-99 to HLA-DR2 and IL-2 and is a tool for MS research. The peptide antagonist is a 15-mer peptide that competes with Myelin Basic Protein MBP (85-99), the immunodominant epitope of MBP and major candidate autoantigen in multiple sclerosis (MS).