3-Benzidino-6-(4-chlorophenyl)pyridazine

• 产品号: B6936
• CAS号: 901773-91-9
• 分子式: C22H17ClN4
• 分子量: 372.85018
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: 3-Benzidino-6-(4-chlorophenyl)pyridazine
• IUPAC标准名: N-[4-(4-aminophenyl)phenyl]-6-(4-chlorophenyl)pyridazin-3-amine
• IUPAC传统名: N-[4-(4-aminophenyl)phenyl]-6-(4-chlorophenyl)pyridazin-3-amine
• 别名: BCP

产品登记号

• MDL号: MFCD11046030
• CAS号: 901773-91-9

产品性质

• 联合国危险货物等级: 6.1
• 联合国危险货物编号: 2811
• 联合国危险货物包装类别(PG): 3
• 德国WGK号: 3
• GHS警示词: Danger
• GHS危险声明: H301
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS警示性声明: P301 + P310
• RID/ADR: UN 2811 6.1/PG 3
• 危险公开号: 22
• 保存温度: 2-8°C
• Empirical Formula (Hill Notation): C22H17N4Cl
• 纯度: ≥98% (HPLC)
• 外观: light yellow solid
• 溶解度: DMSO: >14 mg/mL

产品详细信息

详细说明 (English)

Biochem/physiol Actions
3-Benzidino-6-(4-chlorophenyl)pyridazine is an inhibitor of delayed rectifier and transient outward potassium currents. The IC50 values for the blocking action of BCP on IKDR and IKA was calculated as 7.13 μM and 0.55 μM, respectively in acutely isolated rat hippocampal pyramidal neurons by using whole-cell patch-clamp technique. The parent compound, minaprine (Cat. No. M3157), has selective affinity for M1 muscarinic receptors and possesses memory-enhancing properties and also acts as an antidepressant.

详细说明 (简体中文)

Biochem/physiol Actions
3-Benzidino-6-(4-chlorophenyl)pyridazine is an inhibitor of delayed rectifier and transient outward potassium currents. The IC50 values for the blocking action of BCP on IKDR and IKA was calculated as 7.13 μM and 0.55 μM, respectively in acutely isolated rat hippocampal pyramidal neurons by using whole-cell patch-clamp technique. The parent compound, minaprine (Cat. No. M3157), has selective affinity for M1 muscarinic receptors and possesses memory-enhancing properties and also acts as an antidepressant.