Azelnidipine

• 产品号: A7106
• CAS号: 123524-52-7
• 分子式: C33H34N4O6
• 分子量: 582.64626
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Azelnidipine
• IUPAC标准名: 3-[1-(diphenylmethyl)azetidin-3-yl] 5-propan-2-yl 2-amino-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
• IUPAC传统名: azelnidipine
• 别名: CS-905; 2-Amino-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-[1-(diphenylmethyl)-3-azetidinyl] 5-(1-methylethyl) ester; RS-9054; 2-Amino-1,4-dihydro-6-methyl-4-(3 nitrophenyl)-3,5-pyridinedicarboxylic acid 3-[1-(diphenylmethyl)-3-azetidinyl] 5-(1-methylethyl) ester; Calblock

产品登记号

• MDL号: MFCD00865803
• CAS号: 123524-52-7

产品性质

• Empirical Formula (Hill Notation): C33H34N4O6
• 纯度: ≥98% (HPLC)
• 外观: powder
• 溶解度: DMSO: >10 mg/mL
• GHS警示词: Danger
• GHS危险声明: H302-H318
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P280-P305 + P351 + P338
• 危险公开号: 22-41
• RTECS编号: US7968332
• 安全公开号: 26-39
• 保存温度: room temp
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Application
Azelnidipine is a novel dihydropyridine derivative, a L-type calcium channel blocker, and an antihypertensive. Acute administration of azelnidipine prevents a sudden drop of cardiac function after acute stress. Azelnidipine may have a protective role in inflammation associated with atherosclerosis.
Biochem/physiol Actions
Azelnidipine, a novel dihydropyridine derivative, is a L-type calcium channel blocker and antihypertensive. Unlike other L-type calcium channel blockers, azelnidipine causes minimal stimulation of the sympathetic nervous system despite its significant depressor effect. Azelnidipine may have a protective role in inflammation in atherosclerosis.

详细说明 (简体中文)

Application
Azelnidipine is a novel dihydropyridine derivative, a L-type calcium channel blocker, and an antihypertensive. Acute administration of azelnidipine prevents a sudden drop of cardiac function after acute stress. Azelnidipine may have a protective role in inflammation associated with atherosclerosis.
Biochem/physiol Actions
Azelnidipine, a novel dihydropyridine derivative, is a L-type calcium channel blocker and antihypertensive. Unlike other L-type calcium channel blockers, azelnidipine causes minimal stimulation of the sympathetic nervous system despite its significant depressor effect. Azelnidipine may have a protective role in inflammation in atherosclerosis.