SB-505124 hydrochloride hydrate

• 产品号: S4696
• CAS号: 694433-59-5(freebase)
• 分子式: C20H24ClN3O3
• 分子量: 389.87586
• 纯 度: ≥98% (HPLC)
• 保 存: desiccated

产品别名

• 标题: SB-505124 hydrochloride hydrate
• IUPAC标准名: 2-[4-(2H-1,3-benzodioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl]-6-methylpyridine hydrate hydrochloride
• IUPAC传统名: 2-[5-(2H-1,3-benzodioxol-5-yl)-2-tert-butyl-3H-imidazol-4-yl]-6-methylpyridine hydrate hydrochloride
• 别名: 2-(5-Benzo[1,3]dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrochloride hydrate

产品登记号

• MDL号: MFCD11045901
• CAS号: 694433-59-5(freebase)
• PubChem SID: 24724611

产品性质

• Empirical Formula (Hill Notation): C20H21N3O2 · xHCl · yH2O
• 纯度: ≥98% (HPLC)
• 外观: yellow powder
• 溶解度: DMSO: >10 mg/mL
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 36/37/38
• 安全公开号: 26-36
• 保存条件: desiccated
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
SB-505124 is an inhibitor of activin receptor-like kinase (ALK) 5, also known as transforming growth factor-α type I receptor kinase, with an IC50 of 47 ± 5 nM.

详细说明 (简体中文)

Biochem/physiol Actions
SB-505124 is an inhibitor of activin receptor-like kinase (ALK) 5, also known as transforming growth factor-α type I receptor kinase, with an IC50 of 47 ± 5 nM.