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Pirarubicin

产品号 P8624 公司名称 Sigma Aldrich
CAS号 72496-41-4 公司网站 http://www.sigmaaldrich.com
分子式 C32H37NO12 电 话 1-800-521-8956
分子量 627.63568 传 真
纯 度 ≥95% (HPLC) 电子邮件
保 存 Chembase数据库ID: 72657

产品价格信息

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产品别名

标题
Pirarubicin
IUPAC标准名
(8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-6-methyl-5-(oxan-2-yloxy)oxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione
IUPAC传统名
(8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-6-methyl-5-(oxan-2-yloxy)oxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione
别名
THP

产品登记号

CAS号 72496-41-4
MDL号 MFCD00869742

产品性质

Empirical Formula (Hill Notation) C32H37NO12
纯度 ≥95% (HPLC)
运输包装 wet ice
MSDS下载 下载链接
保存温度 2-8°C
德国WGK号 3

产品详细信息

详细说明 (English)
Biochem/physiol Actions
Anthracycline antibiotic that is an analog of doxorubicin. Antineoplastic. Pirarubicin is transported into cells vial a sodium-dependent nucleoside transporter.1,2 It is used to intercalate DNA and inhibit the activity of topoisomerase II and induce DNA crosslinking.
Application
Pirarubicin, an anthracycline antibiotic, is an anticancer drug. Pirarubicin is used to study synergistic cytotoxicity and apoptosis of cancer cells1,2. It is used to study how to protect multi-drug resistance cells from anthracycline induced cytotoxicity3.
详细说明 (简体中文)
Biochem/physiol Actions
Anthracycline antibiotic that is an analog of doxorubicin. Antineoplastic. Pirarubicin is transported into cells vial a sodium-dependent nucleoside transporter.1,2 It is used to intercalate DNA and inhibit the activity of topoisomerase II and induce DNA crosslinking.
Application
Pirarubicin, an anthracycline antibiotic, is an anticancer drug. Pirarubicin is used to study synergistic cytotoxicity and apoptosis of cancer cells1,2. It is used to study how to protect multi-drug resistance cells from anthracycline induced cytotoxicity3.

参考文献