Application Methicillin is used to study bacterium susceptibility 1, methicillin-resistance in Staphylococcus aureus 2, and to inhibit cell-wall synthesis 3. Biochem/physiol Actions Methicillin inhibits cell wall synthesis. In Legionella pneumophila, methicillin causes the formation of membranous lesions through which cytoplasmic contents are lost 3. |