BAY R3401

• 产品号: B3936
• CAS号: 100276-03-7
• 分子式: C20H22ClNO4
• 分子量: 375.84598
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: BAY R3401
• IUPAC标准名: propan-2-yl 4-(2-chlorophenyl)-1-ethyl-2-methyl-5-oxo-1H,4H,5H,7H-furo[3,4-b]pyridine-3-carboxylate
• IUPAC传统名: isopropyl 4-(2-chlorophenyl)-1-ethyl-2-methyl-5-oxo-4H,7H-furo[3,4-b]pyridine-3-carboxylate
• 别名: 4-(2-Chlorophenyl)-1-ethyl-2-methyl-5-oxo-1,4,5,7-tetrahydrofuro[3,4-b]pyridine-3-carboxylic acid isopropyl ester

产品登记号

• CAS号: 100276-03-7
• MDL号: MFCD08705409
• PubChem SID: 24891741

产品性质

• Empirical Formula (Hill Notation): C20H22ClNO4
• 纯度: ≥98% (HPLC)
• 外观: white solid
• 溶解度: DMSO: soluble15 mg/mL
• GHS警示词: Warning
• GHS危险声明: H302
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• 危险公开号: 22
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Packaging
Light sensitive; store in amber vials.
Biochem/physiol Actions
BAY R3401 is a glycogen phosphorylase inhibitor. The racemic prodrug, BAY R3401, suppresses hepatic glycogenolysis. BAY W1807, the active metabolite of BAY R3401, inhibits muscle glycogen phosphorylase a and b. It has been investigated that the metabolites of BAY R3401 suppress hepatic glycogenolysis by allosteric inhibition and dephosphorylation of phosphorylase a.

详细说明 (简体中文)

包装
Light sensitive; store in amber vials.
Biochem/physiol Actions
BAY R3401 is a glycogen phosphorylase inhibitor. The racemic prodrug, BAY R3401, suppresses hepatic glycogenolysis. BAY W1807, the active metabolite of BAY R3401, inhibits muscle glycogen phosphorylase a and b. It has been investigated that the metabolites of BAY R3401 suppress hepatic glycogenolysis by allosteric inhibition and dephosphorylation of phosphorylase a.