Ifosfamide

• 产品号: I4909
• CAS号: 3778-73-2
• 分子式: C7H15Cl2N2O2P
• 分子量: 261.085961
• 纯 度: ≥98%

产品别名

• 标题: Ifosfamide
• IUPAC标准名: 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]-1,3,2λ^5-oxazaphosphinan-2-one
• IUPAC传统名: ifosfamide
• 别名: N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine-2-oxide; Ifex

产品登记号

• CAS号: 3778-73-2
• EC号: 223-237-3
• MDL号: MFCD00057374

产品性质

• 联合国危险货物等级: 6.1
• 联合国危险货物编号: 2811
• 联合国危险货物包装类别(PG): 3
• 德国WGK号: 3
• GHS警示词: Danger
• GHS危险声明: H301-H319
• 欧盟危险性物质标志: 有毒(Toxic) (T)
• 个人保护装置: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS警示性声明: P301 + P310-P305 + P351 + P338
• RID/ADR: UN 2811 6.1/PG 3
• 危险公开号: 25-36
• RTECS编号: RP6050000
• 安全公开号: 26-45
• 保存温度: 2-8°C
• Empirical Formula (Hill Notation): C7H15Cl2N2O2P
• 纯度: ≥98%
• 运输包装: wet ice

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Ifosfamide is a nitrogen mustard compound that is a structural isomer of cyclophosphamide. Ifosfamide is a prodrug that must be transformed by cytochrome P450 to the biologically active component. It is used as an antineoplastic agent in cancer chemotherapy, but ifosfamide is more likely to cause renal toxicity than cyclophosphamide.

详细说明 (简体中文)

Biochem/physiol Actions
Ifosfamide is a nitrogen mustard compound that is a structural isomer of cyclophosphamide. Ifosfamide is a prodrug that must be transformed by cytochrome P450 to the biologically active component. It is used as an antineoplastic agent in cancer chemotherapy, but ifosfamide is more likely to cause renal toxicity than cyclophosphamide.