Nateglinide

• 产品号: N3538
• CAS号: 105816-04-4
• 分子式: C19H27NO3
• 分子量: 317.42258
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Nateglinide
• IUPAC标准名: (2R)-3-phenyl-2-{[(1r,4r)-4-(propan-2-yl)cyclohexyl]formamido}propanoic acid
• IUPAC传统名: nateglinide
• 别名: Starsis; N-[(trans-4-isopropylcyclohexyl)carbonyl]-D-phenylalanine; Fastic; Starlix

产品登记号

• CAS号: 105816-04-4
• MDL号: MFCD00875706

产品性质

• Empirical Formula (Hill Notation): C19H27NO3
• 纯度: ≥98% (HPLC)
• 外观: white to off-white solid
• 溶解度: DMSO: >5 mg/mL
• 溶解度: H2O: insoluble
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS编号: SQ7318950
• 保存温度: room temp
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Nateglinide is a Kir6.2/SUR1 channel inhibitor and antidiabetic. It is selective for the SUR1 subtype, which is found on pancreatic islet cells. Nateglinide evokes KATP channel-dependent insulin secretion (50-200 μM) in the absence and presence of insulin.

详细说明 (简体中文)

Biochem/physiol Actions
Nateglinide is a Kir6.2/SUR1 channel inhibitor and antidiabetic. It is selective for the SUR1 subtype, which is found on pancreatic islet cells. Nateglinide evokes KATP channel-dependent insulin secretion (50-200 μM) in the absence and presence of insulin.