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Estren

产品号 43620 公司名称 Sigma Aldrich
CAS号 35950-87-9 公司网站 http://www.sigmaaldrich.com
分子式 C18H28O2 电 话 1-800-521-8956
分子量 276.41372 传 真
纯 度 ≥98.0% (TLC) 电子邮件
保 存 Chembase数据库ID: 153940

产品价格信息

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产品别名

标题
Estren
IUPAC标准名
(1S,2R,5R,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.02,7.011,15]heptadec-6-ene-5,14-diol
IUPAC传统名
(1S,2R,5R,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.02,7.011,15]heptadec-6-ene-5,14-diol
别名
4-Estren-3α,17β-diol

产品登记号

CAS号 35950-87-9
MDL号 MFCD00271605

产品性质

Empirical Formula (Hill Notation) C18H28O2
纯度 ≥98.0% (TLC)
熔点 203-207 °C
比旋光度 [α]/D +124±5°, c = 1 in methanol
毒品管制信息 USDEA Schedule III
MSDS下载 下载链接
个人保护装置 Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
德国WGK号 3

产品详细信息

详细说明 (English)
Application
Therapeutic alternative to hormone replacement for osteoporosis of bone mass in both women and men.1,2 Estren increased neuronal viability to a similar extent as that observed with 17α- and 17β-estradiol, by a pathway mediated by protein kinase C.3
Biochem/physiol Actions
Estren is a synthetic steroid that acts via the androgen receptor. It has been shown to directly activate transcription and increases the proliferation of MCF-7 human breast cancer cells in vitro.4
详细说明 (简体中文)
Application
Therapeutic alternative to hormone replacement for osteoporosis of bone mass in both women and men.1,2 Estren increased neuronal viability to a similar extent as that observed with 17α- and 17β-estradiol, by a pathway mediated by protein kinase C.3
Biochem/physiol Actions
Estren is a synthetic steroid that acts via the androgen receptor. It has been shown to directly activate transcription and increases the proliferation of MCF-7 human breast cancer cells in vitro.4

参考文献