GW843682X

• 产品号: G2171
• CAS号: 660868-91-7
• 分子式: C22H18F3N3O4S
• 分子量: 477.4562296
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: GW843682X
• IUPAC标准名: 5-(5,6-dimethoxy-1H-1,3-benzodiazol-1-yl)-3-{[2-(trifluoromethyl)phenyl]methoxy}thiophene-2-carboxamide
• IUPAC传统名: 5-(5,6-dimethoxy-1,3-benzodiazol-1-yl)-3-{[2-(trifluoromethyl)phenyl]methoxy}thiophene-2-carboxamide
• 别名: GW843682; 5-(5,6-dimethoxy-1H-benzimidazol-1-yl)-3-{[2-(trifluoromethyl)-benzyl]oxy}thiophene-2-carboxamide

产品登记号

• MDL号: MFCD09971143
• CAS号: 660868-91-7

产品性质

• Empirical Formula (Hill Notation): C22H18F3N3O4S
• 纯度: ≥98% (HPLC)
• 外观: off-white solid
• 溶解度: DMSO: >10 mg/mL
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335-H413
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 36/37/38
• 安全公开号: 26-36/37
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
GW843682X is a polo-like kinase-1 (PLK1) and polo-like kinase-3 (PLK3) inhibitor with nanomolar activity. It shows potent inhibition of proliferation of a wide variety of tumor cell lines.

详细说明 (简体中文)

Biochem/physiol Actions
GW843682X is a polo-like kinase-1 (PLK1) and polo-like kinase-3 (PLK3) inhibitor with nanomolar activity. It shows potent inhibition of proliferation of a wide variety of tumor cell lines.