5-(4-Phenoxybutoxy)psoralen

• 产品号: P6124
• CAS号: 870653-45-5
• 分子式: C21H18O5
• 分子量: 350.36462
• 纯 度: ≥98% (HPLC)
• 保 存: protect from light

产品别名

• 标题: 5-(4-Phenoxybutoxy)psoralen
• IUPAC标准名: 4-(4-phenoxybutoxy)-7H-furo[3,2-g]chromen-7-one
• IUPAC传统名: 4-(4-phenoxybutoxy)furo[3,2-g]chromen-7-one
• 别名: PAP-1

产品登记号

• CAS号: 870653-45-5
• MDL号: MFCD11114059
• PubChem SID: 24724583

产品性质

• Empirical Formula (Hill Notation): C21H18O5
• 纯度: ≥98% (HPLC)
• 外观: white solid
• 溶解度: DMSO: soluble9 mg/mL
• GHS警示词: Danger
• GHS危险声明: H334
• 个人保护装置: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS警示性声明: P261-P342 + P311
• 危险公开号: 42/43
• 安全公开号: 22-36/37-45
• 保存条件: protect from light
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Selective inhibitor of Kv1.3, voltage-gated K+ channel. PAP-1 (EC50=2 nM) potently inhibits human T effector memory cell proliferation and delayed hypersensitivity. Effective orally or intraperitoneally. 5-(4-Phenoxybutoxy)psoralen has 23-fold selectivity for Kv1.3 over Kv1.5, and 33-125-fold selectivity over other Kv1 family channels.

详细说明 (简体中文)

Biochem/physiol Actions
Selective inhibitor of Kv1.3, voltage-gated K+ channel. PAP-1 (EC50=2 nM) potently inhibits human T effector memory cell proliferation and delayed hypersensitivity. Effective orally or intraperitoneally. 5-(4-Phenoxybutoxy)psoralen has 23-fold selectivity for Kv1.3 over Kv1.5, and 33-125-fold selectivity over other Kv1 family channels.