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DCPIB_分子结构_CAS_82749-70-0)
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DCPIB

产品号 D4068 公司名称 Sigma Aldrich
CAS号 82749-70-0 公司网站 http://www.sigmaaldrich.com
分子式 C22H28Cl2O4 电 话 1-800-521-8956
分子量 427.36132 传 真
纯 度 ≥98% (HPLC) 电子邮件
保 存 under inert gas Chembase数据库ID: 153920

产品价格信息

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产品别名

标题
DCPIB
IUPAC标准名
4-[(2-butyl-6,7-dichloro-2-cyclopentyl-1-oxo-2,3-dihydro-1H-inden-5-yl)oxy]butanoic acid
IUPAC传统名
4-[(2-butyl-6,7-dichloro-2-cyclopentyl-1-oxo-3H-inden-5-yl)oxy]butanoic acid
别名
4-(2-butyl-6,7-dichloro-2-cyclopentylindan-1-on-5-yl)oxybutyric acid

产品登记号

MDL号 MFCD07783995
PubChem SID 24724462
CAS号 82749-70-0

产品性质

Empirical Formula (Hill Notation) C22H28Cl2O4
纯度 ≥98% (HPLC)
外观 white solid
溶解度 DMSO: >40 mg/mL
GHS危险品标识 GHS05
GHS危险品标识 GHS06
GHS警示词 Danger
GHS危险声明 H301-H318-H413
欧盟危险性物质标志 有毒(Toxic) 有毒(Toxic) (T)
MSDS下载 下载链接
个人保护装置 Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
GHS警示性声明 P280-P301 + P310-P305 + P351 + P338
RID/ADR UN 2811 6.1/PG 3
危险公开号 25-41
安全公开号 26-36/39-45
保存条件 under inert gas
保存温度 2-8°C
联合国危险货物等级 6.1
联合国危险货物编号 2811
联合国危险货物包装类别(PG) 3
德国WGK号 3

产品详细信息

详细说明 (English)
Biochem/physiol Actions
DCPIB is a potent inhibitor of the volume-sensitive anion channel (VSAC). IC50 = 4.1μM ) versus ICl,swell in calf pulmonary artery endothelial (CPAE) cells. DCPIB does not inhibit CPAE cell ICl,Ca; hCFTR; nor guinea pig ICl,PKA, IKr, IKs,IKl, INa and ICa. DCPIB inhibition is reversible and voltage independent. ICl,swell is believed to be important in cardiovascular function. Studies have been limited by the lack of specific ligands.
详细说明 (简体中文)
Biochem/physiol Actions
DCPIB is a potent inhibitor of the volume-sensitive anion channel (VSAC). IC50 = 4.1μM ) versus ICl,swell in calf pulmonary artery endothelial (CPAE) cells. DCPIB does not inhibit CPAE cell ICl,Ca; hCFTR; nor guinea pig ICl,PKA, IKr, IKs,IKl, INa and ICa. DCPIB inhibition is reversible and voltage independent. ICl,swell is believed to be important in cardiovascular function. Studies have been limited by the lack of specific ligands.

参考文献