Fulvestrant

• 产品号: I4409
• CAS号: 129453-61-8
• 分子式: C32H47F5O3S
• 分子量: 606.770796
• 纯 度: >98% (HPLC)

产品别名

• 标题: Fulvestrant
• IUPAC标准名: (1S,9R,10R,11S,14S,15S)-15-methyl-9-[9-(4,4,5,5,5-pentafluoropentanesulfinyl)nonyl]tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-2,4,6-triene-5,14-diol
• IUPAC传统名: fulvestrant
• 别名: Faslodex; ZD 9238; ZD 182780; ICI 182,780; (7a,17b)-7-[9-[(4,4,5,5,5pentafluoropentyl)Sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17-diol; ZM 182780

产品登记号

• MDL号: MFCD00903953
• CAS号: 129453-61-8

产品性质

• Empirical Formula (Hill Notation): C32H47F5O3S
• 纯度: >98% (HPLC)
• 外观: powder
• 溶解度: DMSO: >5 mg/mL
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS编号: KG7623000
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Fulvestrant (ICI 182,780) is a selective estrogen receptor down-regulator (SERD). Fulvestrant is a high affinity estrogen receptor antagonist. IC50 = 0.29 nM. Fulvestrant is the first "pure" antiestrogen with no agonistic activity both in vitro and in vivo.

详细说明 (简体中文)

Biochem/physiol Actions
Fulvestrant (ICI 182,780) is a selective estrogen receptor down-regulator (SERD). Fulvestrant is a high affinity estrogen receptor antagonist. IC50 = 0.29 nM. Fulvestrant is the first "pure" antiestrogen with no agonistic activity both in vitro and in vivo.