IRAK-1/4 Inhibitor I

• 产品号: I5409
• 分子式: C20H21N5O4
• 分子量: 395.41184
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: IRAK-1/4 Inhibitor I
• IUPAC标准名: N-{1-[2-(morpholin-4-yl)ethyl]-1H-1,3-benzodiazol-2-yl}-3-nitrobenzamide
• IUPAC传统名: N-{1-[2-(morpholin-4-yl)ethyl]-1,3-benzodiazol-2-yl}-3-nitrobenzamide
• 别名: N-(2-Morpholinylethyl)-2-(3-nitrobenzoylamido)-benzimidazole; 1-(2-(4-Morpholinyl)ethyl)-2-(3-nitrobenzoylamino)benzimidazole

产品登记号

• MDL号: MFCD09752602

产品性质

• Empirical Formula (Hill Notation): C20H21N5O4
• 纯度: ≥98% (HPLC)
• 外观: off-white to light yellow solid
• 溶解度: DMSO: ≥5 mg/mL
• GHS警示词: Danger
• GHS危险声明: H301-H315-H319-H335
• 欧盟危险性物质标志: 有毒(Toxic) (T)
• 个人保护装置: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS警示性声明: P261-P301 + P310-P305 + P351 + P338
• RID/ADR: UN 2811 6.1/PG 3
• 危险公开号: 25-36/37/38
• 安全公开号: 26-36/37-45
• 保存温度: 2-8°C
• 联合国危险货物等级: 6.1
• 联合国危险货物编号: 2811
• 联合国危险货物包装类别(PG): 3
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
IRAK-1/4 Inhibitor I is a novel benzimidazole that is a potent inhibitor of interleukin-1 receptor-associated kinases 1/4 (IRAK 1/4). IC50 values were 300 nM and 200 nM for IRAK-1 and -4, respectively, and >10,000 nM for a panel of 27 other kinases tested.

详细说明 (简体中文)

Biochem/physiol Actions
IRAK-1/4 Inhibitor I is a novel benzimidazole that is a potent inhibitor of interleukin-1 receptor-associated kinases 1/4 (IRAK 1/4). IC50 values were 300 nM and 200 nM for IRAK-1 and -4, respectively, and >10,000 nM for a panel of 27 other kinases tested.