PRL-3 Inhibitor I

• 产品号: P0108
• CAS号: 893449-38-2
• 分子式: C17H11Br2NO2S2
• 分子量: 485.21274
• 纯 度: ≥98% (HPLC)
• 保 存: protect from light

产品别名

• 标题: PRL-3 Inhibitor I
• IUPAC标准名: 5-({5-bromo-2-[(2-bromophenyl)methoxy]phenyl}methylidene)-2-sulfanylidene-1,3-thiazolidin-4-one
• IUPAC传统名: 5-({5-bromo-2-[(2-bromophenyl)methoxy]phenyl}methylidene)-2-sulfanylidene-1,3-thiazolidin-4-one
• 别名: 5-[[5-bromo-2-[(2-bromophenyl)methoxy]phenyl]methylene]-2-thioxo-4-thiazolidinone; Phosphatase of regenerating liver-3, Inhibitor I

产品登记号

• MDL号: MFCD11045303
• CAS号: 893449-38-2

产品性质

• Empirical Formula (Hill Notation): C17H11Br2NO2S2
• 纯度: ≥98% (HPLC)
• 外观: yellow solid
• 溶解度: DMSO: >10 mg/mL
• 溶解度: H2O: <2 mg/mL
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335-H410
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 欧盟危险性物质标志: 环境危害性(Nature polluting) (N)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P261-P273-P305 + P351 + P338-P501
• RID/ADR: UN 3077 9/PG 3
• 危险公开号: 36/37/38-50/53
• 安全公开号: 26-36/37-60-61
• 保存条件: protect from light
• 保存温度: -20°C
• 联合国危险货物等级: 9
• 联合国危险货物编号: 3077
• 联合国危险货物包装类别(PG): 3
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
PRL-3 Inhibitor I is a rhodanine derivative with an IC50 value of 0.9 μM against phosphatase of regenerating liver-3 (PRL-3), a nonclassical protein tyrosine phosphatase that has recently been shown to be involved in cancer metastasis. PRL-3 Inhibitor I reduced the invasiveness of B16F10 melanoma cells in a cell based assay.

详细说明 (简体中文)

Biochem/physiol Actions
PRL-3 Inhibitor I is a rhodanine derivative with an IC50 value of 0.9 μM against phosphatase of regenerating liver-3 (PRL-3), a nonclassical protein tyrosine phosphatase that has recently been shown to be involved in cancer metastasis. PRL-3 Inhibitor I reduced the invasiveness of B16F10 melanoma cells in a cell based assay.