M344

• 产品号: M5820
• CAS号: 251456-60-7
• 分子式: C16H25N3O3
• 分子量: 307.388
• 纯 度: ≥98% (HPLC)
• 保 存: protect from light

产品别名

• 标题: M344
• IUPAC标准名: 7-{[4-(dimethylamino)phenyl]formamido}-N-hydroxyheptanamide
• IUPAC传统名: 7-{[4-(dimethylamino)phenyl]formamido}-N-hydroxyheptanamide
• 别名: N-Hydroxy-7-(4-dimethylaminobenzoyl)-aminoheptanamide; MS 344, D237; 4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]-benzamide

产品登记号

• MDL号: MFCD03453554
• CAS号: 251456-60-7

产品性质

• Empirical Formula (Hill Notation): C16H25N3O3
• 纯度: ≥98% (HPLC)
• 外观: white to beige powder
• 溶解度: DMSO: soluble10 mg/mL, clear
• 保存条件: protect from light
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
M344 is a HDAC inhibitor; subtype selective for HDAC6 over HDAC1. M344 inhibits HDAC (IC50 = 100 nM) and also inhibits hyperacetylation of histone H4, terminal cell differentiation, transcription (γ-globin), and tumor cell death.

详细说明 (简体中文)

Biochem/physiol Actions
M344 is a HDAC inhibitor; subtype selective for HDAC6 over HDAC1. M344 inhibits HDAC (IC50 = 100 nM) and also inhibits hyperacetylation of histone H4, terminal cell differentiation, transcription (γ-globin), and tumor cell death.