Mephetyl tetrazole

• 产品号: M7945
• CAS号: 916923-10-9
• 分子式: C20H22N4O
• 分子量: 334.41488
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Mephetyl tetrazole
• IUPAC标准名: 1-[2-(4-methoxyphenyl)ethyl]-5-[1-(4-methylphenyl)cyclopropyl]-1H-1,2,3,4-tetrazole
• IUPAC传统名: 1-[2-(4-methoxyphenyl)ethyl]-5-[1-(4-methylphenyl)cyclopropyl]-1,2,3,4-tetrazole
• 别名: 1-[2-(4-Methoxyphenyl)ethyl]-5-(1-p-tolylcyclopropyl)-1H-tetrazole

产品登记号

• CAS号: 916923-10-9
• MDL号: MFCD11045297

产品性质

• Empirical Formula (Hill Notation): C20H22N4O
• 纯度: ≥98% (HPLC)
• 外观: pale yellow oil
• 溶解度: DMSO: >5 mg/mL
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Mephetyl tetrazole is a potent and selective Kv1.5 potassium channel blocker. IC50 = 330 nM; shows selective atrial prolongation (40%) of effective refractory period (ERP), but no effect on ventricular ERP Kv1.5 channel is a molecular target for the treatment of atrial fibrillation.

详细说明 (简体中文)

Biochem/physiol Actions
Mephetyl tetrazole is a potent and selective Kv1.5 potassium channel blocker. IC50 = 330 nM; shows selective atrial prolongation (40%) of effective refractory period (ERP), but no effect on ventricular ERP Kv1.5 channel is a molecular target for the treatment of atrial fibrillation.