Supercinnamaldehyde

• 产品号: S3322
• CAS号: 70351-51-8
• 分子式: C12H11NO2
• 分子量: 201.22124
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Supercinnamaldehyde
• IUPAC标准名: 1-methyl-3-(2-oxopropylidene)-2,3-dihydro-1H-indol-2-one
• IUPAC传统名: 1-methyl-3-(2-oxopropylidene)indol-2-one
• 别名: 1,3-Dihydro-1-methyl-3-(2-oxopropylidene)-2H-Indol-2-one

产品登记号

• CAS号: 70351-51-8
• MDL号: MFCD08530327

产品性质

• Empirical Formula (Hill Notation): C12H11NO2
• 纯度: ≥98% (HPLC)
• 外观: red solid
• 溶解度: H2O: insoluble <2 mg/mL
• 溶解度: DMSO: >20 mg/mL
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 36/37/38-52/53
• 安全公开号: 26-36/37-61
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Caution
Air-sensitive
Biochem/physiol Actions
Supercinnamaldehyde is a transient receptor potential ankyrin 1 (TRPA1) activator; EC50 = 0.8 μM; derivative of cinnamaldehyde; covalently binds to and activates TRPA1 receptor (expressed in nociceptive neurons) by modifying its cysteine residues. Covalent modification of reactive cysteines within TRPA1 can cause channel activation, rapidly signaling potential tissue damage through the pain pathway.

详细说明 (简体中文)

Caution
Air-sensitive
Biochem/physiol Actions
Supercinnamaldehyde is a transient receptor potential ankyrin 1 (TRPA1) activator; EC50 = 0.8 μM; derivative of cinnamaldehyde; covalently binds to and activates TRPA1 receptor (expressed in nociceptive neurons) by modifying its cysteine residues. Covalent modification of reactive cysteines within TRPA1 can cause channel activation, rapidly signaling potential tissue damage through the pain pathway.