N-(3-Pyridyl)indomethacinamide

• 产品号: P0865
• 分子式: C24H20ClN3O3
• 分子量: 433.8869
• 纯 度: ≥98%

产品别名

• 标题: N-(3-Pyridyl)indomethacinamide
• IUPAC标准名: 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-(pyridin-3-yl)acetamide
• IUPAC传统名: 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-N-(pyridin-3-yl)acetamide
• 别名: N-(3-Pyridyl)-1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetamide; N-3PyIA

产品登记号

• MDL号: MFCD02683393

产品性质

• Empirical Formula (Hill Notation): C24H20N3O3Cl
• 纯度: ≥98%
• 运输包装: wet ice
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Potent and selective reversible cyclooxygenase-2 (COX-2) inhibitor (IC50 = 0.1 μM, human recombinant); about 300-fold less potent as an inhibitor of human recombinant COX-1. Not as selective with natural ovine COX (IC50 = 75 μM for COX-1 and 50 μM for COX-2).

详细说明 (简体中文)

Biochem/physiol Actions
Potent and selective reversible cyclooxygenase-2 (COX-2) inhibitor (IC50 = 0.1 μM, human recombinant); about 300-fold less potent as an inhibitor of human recombinant COX-1. Not as selective with natural ovine COX (IC50 = 75 μM for COX-1 and 50 μM for COX-2).