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BIO

产品号 B1686 公司名称 Sigma Aldrich
CAS号 667463-62-9 公司网站 http://www.sigmaaldrich.com
分子式 C16H10BrN3O2 电 话 1-800-521-8956
分子量 356.1735 传 真
纯 度 ≥98% (HPLC) 电子邮件
保 存 protect from light Chembase数据库ID: 153822

产品价格信息

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产品别名

标题
BIO
IUPAC标准名
6-bromo-3-[3-(hydroxyimino)-2,3-dihydro-1H-indol-2-ylidene]-2,3-dihydro-1H-indol-2-one
IUPAC传统名
6-bromo-3-[3-(hydroxyimino)-1H-indol-2-ylidene]-1H-indol-2-one
别名
6BIO
6-BIO
(2’Z,3’E)-6-Bromoindirubin-3′-oxime

产品登记号

CAS号 667463-62-9
PubChem SID 24724412
MDL号 MFCD08705318

产品性质

Empirical Formula (Hill Notation) C16H10BrN3O2
纯度 ≥98% (HPLC)
运输包装 wet ice
外观 dark red powder
溶解度 DMSO: >5 mg/mL
GHS危险品标识 GHS07
GHS警示词 Warning
GHS危险声明 H315-H319-H335
欧盟危险性物质标志 刺激性(Irritant) 刺激性(Irritant) (Xi)
MSDS下载 下载链接
个人保护装置 dust mask type N95 (US), Eyeshields, Gloves
GHS警示性声明 P261-P305 + P351 + P338
危险公开号 36/37/38
安全公开号 26-36
保存条件 protect from light
保存温度 2-8°C
德国WGK号 3

产品详细信息

详细说明 (English)
Packaging
air sensitive
Legal Information
Product is sold for research and laboratory purposes in vitro and may not be used for any in vivo or therapeutic uses in humans, veterinary applications, or to make chemical derivatives.
Biochem/physiol Actions
6-bromoindirubin-3′-oxime (BIO) is a potent, reversible and ATP-competitive GSK-3α/β inhibitor and the first pharmacological agent shown to maintain self-renewal in human and mouse embryonic stem cells. Human embryonic stem cells (hESCs) are maintained in the undifferentiated state through treatment with a GSK-3 inhibitor, BIO, under a feeder-free condition.
详细说明 (简体中文)
包装
air sensitive
Legal Information
Product is sold for research and laboratory purposes in vitro and may not be used for any in vivo or therapeutic uses in humans, veterinary applications, or to make chemical derivatives.
Biochem/physiol Actions
6-bromoindirubin-3′-oxime (BIO) is a potent, reversible and ATP-competitive GSK-3α/β inhibitor and the first pharmacological agent shown to maintain self-renewal in human and mouse embryonic stem cells. Human embryonic stem cells (hESCs) are maintained in the undifferentiated state through treatment with a GSK-3 inhibitor, BIO, under a feeder-free condition.

参考文献