SB 202190

• 产品号: S7067
• CAS号: 152121-30-7
• 分子式: C20H14FN3O
• 分子量: 331.3430632
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: SB 202190
• IUPAC标准名: 4-[4-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-imidazol-2-yl]phenol
• IUPAC传统名: 4-[4-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-imidazol-2-yl]phenol
• 别名: 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole

产品登记号

• PubChem SID: 24278272
• CAS号: 152121-30-7
• MDL号: MFCD00941964

产品性质

• Empirical Formula (Hill Notation): C20H14FN3O
• 纯度: ≥98% (HPLC)
• 相关基因信息: human ... MAPK14(1432)
• 外观: pale yellow
• 溶解度: DMSO: soluble30 mg/mL
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 36/37/38
• 安全公开号: 26-36/37
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
SB 202190 is a highly selective, potent and cell permeable inhibitor of p38 MAP kinase. SB 202190 binds within the ATP pocket of the active kinase (Kd = 38 nM, as measured in recombinant human p38), and selectively inhibits the p38α and β isoforms.
Legal Information
Sold for research purposes under agreement from Glaxo-Smith-Kline

详细说明 (简体中文)

Biochem/physiol Actions
SB 202190 is a highly selective, potent and cell permeable inhibitor of p38 MAP kinase. SB 202190 binds within the ATP pocket of the active kinase (Kd = 38 nM, as measured in recombinant human p38), and selectively inhibits the p38α and β isoforms.
Legal Information
Sold for research purposes under agreement from Glaxo-Smith-Kline