(Z)-Guggulsterone

• 产品号: G5168
• CAS号: 39025-23-5
• 分子式: C21H28O2
• 分子量: 312.44582
• 纯 度: ≥89% (HPLC)

产品别名

• 标题: (Z)-Guggulsterone
• IUPAC标准名: (1S,2R,10R,11S,15S)-14-ethylidene-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-6-ene-5,13-dione
• IUPAC传统名: (1S,2R,10R,11S,15S)-14-ethylidene-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-6-ene-5,13-dione
• 别名: (17Z)-Pregna-4,17(20)-diene-3,16-dione; 4,17(20)-trans-Pregnadiene-3,16-dione

产品登记号

• MDL号: MFCD01310757
• PubChem SID: 24278392
• CAS号: 39025-23-5

产品性质

• Empirical Formula (Hill Notation): C21H28O2
• 杂质: ≤5.4% E-form
• 纯度: ≥89% (HPLC)
• 外观: light yellow powder
• 溶解度: DMSO: soluble5 mg/mL
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• 危险公开号: 37
• 安全公开号: 36
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
(Z)-Guggulsterone is a natural product that lowers cholesterol due to its function as an antagonist ligand for the bile acid receptor. (Z)-Guggulsterone is a nuclear hormone receptor that regulates the transcription of several genes involved in cholesterol metabolism and plays a role in cholesterol level regulation. (Z)-Guggulsterone is also a selective farnesoid X receptor (FXR) modulator.

详细说明 (简体中文)

Biochem/physiol Actions
(Z)-Guggulsterone is a natural product that lowers cholesterol due to its function as an antagonist ligand for the bile acid receptor. (Z)-Guggulsterone is a nuclear hormone receptor that regulates the transcription of several genes involved in cholesterol metabolism and plays a role in cholesterol level regulation. (Z)-Guggulsterone is also a selective farnesoid X receptor (FXR) modulator.