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氯霉素

产品号 C1863 公司名称 Sigma Aldrich
CAS号 56-75-7 公司网站 http://www.sigmaaldrich.com
分子式 C11H12Cl2N2O5 电 话 1-800-521-8956
分子量 323.12938 传 真
纯 度 电子邮件
保 存 Chembase数据库ID: 53504

产品价格信息

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产品别名

标题
Chloramphenicol
IUPAC标准名
2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
IUPAC传统名
chloromycetin
别名
D(-)-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-β-(4-nitrophenyl)ethyl]acetamide
D-(-)-threo-2-Dichloroacetamido-1-(4-nitrophenyl)-1,3-propanediol
D-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-4-nitrophenethyl]acetamide
D-(-)-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-β-(4-nitrophenyl)ethyl]acetamide
Chloromycetin

产品登记号

MDL号 MFCD00078159
Beilstein号 2225532
PubChem SID 24892441
CAS号 56-75-7
EC号 200-287-4

产品性质

级别 Biotechnology Performance Certified
杂质 endotoxin, tested
线性分子式 Cl2CHCONHCH(CH2OH)CH(OH)C6H4NO2
适用性 suitable for plant cell culture
相关基因信息 human ... CYP1A2(1544)
熔点 148-150 °C(lit.)
GHS危险品标识 GHS08
GHS警示词 Danger
GHS危险声明 H350
欧盟危险性物质标志 有毒(Toxic) 有毒(Toxic) (T)
MSDS下载 下载链接
个人保护装置 Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
GHS警示性声明 P201-P308 + P313
危险公开号 45
RTECS编号 AB6825000
安全公开号 53-45
德国WGK号 3

产品详细信息

详细说明 (English)
Application
Used as a seletion agent for transformed cells containing chloramphenicol resistance genes.
Biochem/physiol Actions
Mode of Action: Inhibits translation on the 50S ribosomal subunit at the peptidyltransferase step (elongation inhibition). Bacteriostatic.Mode of Resistance: Acetylation by chloramphenicol acetyltransferase (cat gene).
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information
详细说明 (简体中文)
Application
Used as a seletion agent for transformed cells containing chloramphenicol resistance genes.
Biochem/physiol Actions
Mode of Action: Inhibits translation on the 50S ribosomal subunit at the peptidyltransferase step (elongation inhibition). Bacteriostatic.Mode of Resistance: Acetylation by chloramphenicol acetyltransferase (cat gene).
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information

参考文献