Dolastatin 15

• 产品号: D5566
• CAS号: 123884-00-4
• 分子式: C45H68N6O9
• 分子量: 837.05622
• 纯 度: ≥95%

产品别名

• 标题: Dolastatin 15
• IUPAC标准名: (2S)-1-[(2S)-2-benzyl-3-methoxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl]-3-methyl-1-oxobutan-2-yl (2S)-1-[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-(dimethylamino)-3-methylbutanamido]-N,3-dimethylbutanamido]-3-methylbutanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylate
• IUPAC传统名: (2S)-1-[(2S)-2-benzyl-3-methoxy-5-oxo-2H-pyrrol-1-yl]-3-methyl-1-oxobutan-2-yl (2S)-1-[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-(dimethylamino)-3-methylbutanamido]-N,3-dimethylbutanamido]-3-methylbutanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylate
• 别名: (5S)-1-[(2S)-O-(N,N-Val-Val-N-Me-Val-Pro-Pro)-2-hydroxyisovaleryl]-2-oxo-4-methoxy-5-benzyl-3-pyrroline

产品登记号

• MDL号: MFCD00236968
• CAS号: 123884-00-4
• PubChem SID: 24893943

产品性质

• Empirical Formula (Hill Notation): C45H68N6O9
• 纯度: ≥95%
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Amino Acid Sequence
Val-Val-NMe-Val-Pro-Pro-2-hydroxyisovaleryl-2-oxo-4-methoxy-5-benzyl-3-pyrroline
Application
An anti-neoplastic pseudopeptide originally isolated from the sea hare Dolabella auricularia. Reported to interact with tubulin and induce apoptosis. Potent inhibitor of the proliferation of murine and cancer cell lines as well as of hematopoietic progenitor cells.

详细说明 (简体中文)

Amino Acid Sequence
Val-Val-NMe-Val-Pro-Pro-2-hydroxyisovaleryl-2-oxo-4-methoxy-5-benzyl-3-pyrroline
Application
An anti-neoplastic pseudopeptide originally isolated from the sea hare Dolabella auricularia. Reported to interact with tubulin and induce apoptosis. Potent inhibitor of the proliferation of murine and cancer cell lines as well as of hematopoietic progenitor cells.