Kasugamycin hydrochloride from Streptomyces kasugaensis

• 产品号: K4013
• CAS号: 19408-46-9
• 分子式: C14H26ClN3O9
• 分子量: 415.82394
• 纯 度: ≥90% (HPLC)

产品别名

• 标题: Kasugamycin hydrochloride from Streptomyces kasugaensis
• IUPAC标准名: {N-[(2R,3S,5S,6R)-5-amino-2-methyl-6-{[(1S,2R,3S,4R,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}oxan-3-yl]carbamimidoyl}formic acid hydrochloride
• IUPAC传统名: kasugamycin hydrochloride
• 别名: 3-O-[2-Amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-D-arabino-hexopyranosyl]-D-chiro-inositol

产品登记号

• CAS号: 19408-46-9
• MDL号: MFCD00058459
• PubChem SID: 24896238

产品性质

• Empirical Formula (Hill Notation): C14H25N3O9 · HCl
• 纯度: ≥90% (HPLC)
• 溶解度: H2O: soluble
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS编号: NM7521800
• 保存温度: 2-8°C
• 德国WGK号: 2

产品详细信息

详细说明 (English)

Application
Kasugamycin (Ksg) is an aminoglycoside antibiotic isolated from Streptomyces kasugaensis. It is used to study ribosome structure and interactions near the m26A m26A sequence1. It is used to study the mechanisms of kasugamycin resistance2.
Biochem/physiol Actions
kasugamycin binds within the mRNA channel of the 30S subunit between the universally conserved G926 and A794 nucleotides in 16S ribosomal RNA2. Inhibits protein synthesis and binding of aminoacyl-SRNA to the ribosomes in fungi. Induces f-met-tRNA dissociation from P-site of 30S subunit.

详细说明 (简体中文)

Application
Kasugamycin (Ksg) is an aminoglycoside antibiotic isolated from Streptomyces kasugaensis. It is used to study ribosome structure and interactions near the m26A m26A sequence1. It is used to study the mechanisms of kasugamycin resistance2.
Biochem/physiol Actions
kasugamycin binds within the mRNA channel of the 30S subunit between the universally conserved G926 and A794 nucleotides in 16S ribosomal RNA2. Inhibits protein synthesis and binding of aminoacyl-SRNA to the ribosomes in fungi. Induces f-met-tRNA dissociation from P-site of 30S subunit.