Kenpaullone

• 产品号: K3888
• CAS号: 142273-20-9
• 分子式: C16H11BrN2O
• 分子量: 327.17534
• 纯 度: ≥99%

产品别名

• 标题: Kenpaullone
• IUPAC标准名: 14-bromo-8,18-diazatetracyclo[9.7.0.0^2,^7.0^1^2,^1^7]octadeca-1(11),2,4,6,12,14,16-heptaen-9-one
• IUPAC传统名: 14-bromo-8,18-diazatetracyclo[9.7.0.0^2,^7.0^1^2,^1^7]octadeca-1(11),2,4,6,12,14,16-heptaen-9-one
• 别名: 9-Bromo-7,12-dihydro-indolo-[3,2-d]-[1]benzazepin-6(5H)-one; NSC 664704

产品登记号

• PubChem SID: 24278507
• MDL号: MFCD02683595
• CAS号: 142273-20-9

产品性质

• Empirical Formula (Hill Notation): C16H11BrN2O
• 纯度: ≥99%
• 相关基因信息: human ... CDC2(983)mouse ... Gsk3b(56637)rat ... Gsk3b(84027)
• 外观: yellow
• 溶解度: DMSO: soluble18 mg/mL, clear, yellow
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 36/37/38
• 安全公开号: 26-36
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Kenpaullone is a potent inhibitor of CDK1/cyclin B (IC50 = 400 nM), CDK2/cyclin A (IC50 = 680 nM), CDK2/cyclin E (IC50 = 7.5 uM) and CDK5/p25 (IC50 = 850 nM).
Packaging
Store under argon

详细说明 (简体中文)

Biochem/physiol Actions
Kenpaullone is a potent inhibitor of CDK1/cyclin B (IC50 = 400 nM), CDK2/cyclin A (IC50 = 680 nM), CDK2/cyclin E (IC50 = 7.5 uM) and CDK5/p25 (IC50 = 850 nM).
包装
Store under argon