MDL 28170

• 产品号: M6690
• CAS号: 88191-84-8
• 分子式: C22H26N2O4
• 分子量: 382.45284
• 纯 度: ≥95% (HPLC)

产品别名

• 标题: MDL 28170
• IUPAC标准名: benzyl N-[(1S)-2-methyl-1-[(1-oxo-3-phenylpropan-2-yl)carbamoyl]propyl]carbamate
• IUPAC传统名: benzyl N-[(1S)-2-methyl-1-[(1-oxo-3-phenylpropan-2-yl)carbamoyl]propyl]carbamate
• 别名: Calpain Inhibitor III

产品登记号

• PubChem SID: 24278565
• CAS号: 88191-84-8
• MDL号: MFCD00798796

产品性质

• 主要成分: Peptide Content, >90%
• Empirical Formula (Hill Notation): C22H26N2O4
• 纯度: ≥95% (HPLC)
• 运输包装: wet ice
• 相关基因信息: human ... CAPN1(823), CAPN2(824)
• 溶解度: DMSO: soluble26 mg/mL
• 溶解度: H2O: insoluble
• 溶解度: methanol: soluble
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Amino Acid Sequence
Z-Val-Phe-al
Biochem/physiol Actions
MDL 28170 is a potent cell permeable calpain I and II inhibitor; reduces capsaicin-mediated cell death in cultured dorsal root ganglion neurons. Reduced occurrence of apoptosis in H2O2 and A23187 treated PC12 cells. γ-secretase-inhibitor.

详细说明 (简体中文)

Amino Acid Sequence
Z-Val-Phe-al
Biochem/physiol Actions
MDL 28170 is a potent cell permeable calpain I and II inhibitor; reduces capsaicin-mediated cell death in cultured dorsal root ganglion neurons. Reduced occurrence of apoptosis in H2O2 and A23187 treated PC12 cells. γ-secretase-inhibitor.