Mdivi-1

• 产品号: M0199
• CAS号: 338967-87-6
• 分子式: C15H10Cl2N2O2S
• 分子量: 353.2231
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Mdivi-1
• IUPAC标准名: 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-3,4-dihydroquinazolin-4-one
• IUPAC传统名: 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanylquinazolin-4-one
• 别名: 3-(2,4-Dichloro-5-methoxyphenyl)-2,3-dihydro-2-thioxo-4(1H)-quinazolinone; 3-(2,4-Dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone

产品登记号

• MDL号: MFCD00974506
• CAS号: 338967-87-6

产品性质

• Empirical Formula (Hill Notation): C15H10Cl2N2O2S
• 纯度: ≥98% (HPLC)
• 运输包装: wet ice
• 外观: powder
• 溶解度: DMSO: >20 mg/mL
• RID/ADR: UN 2811 6.1/PG 3
• 保存温度: -20°C
• 联合国危险货物等级: 6.1
• 联合国危险货物编号: 2811
• 联合国危险货物包装类别(PG): 3
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Mdivi-1 is a cell-permeable selective inhibitor of mitochondrial division DRP (dynamin-related GTPase) and inhibitor of the mitochondrial division dynamin (Dnm1). Mitochondrial fusion and division play important roles in the regulation of apoptosis. Mdivi-1 is the first selective inhibitor of mitochondrial division dynamins. In principle, Mdivi-1 represents a class of therapeutics for stroke, myocardial infarction, and neurodegenerative diseases.

详细说明 (简体中文)

Biochem/physiol Actions
Mdivi-1 is a cell-permeable selective inhibitor of mitochondrial division DRP (dynamin-related GTPase) and inhibitor of the mitochondrial division dynamin (Dnm1). Mitochondrial fusion and division play important roles in the regulation of apoptosis. Mdivi-1 is the first selective inhibitor of mitochondrial division dynamins. In principle, Mdivi-1 represents a class of therapeutics for stroke, myocardial infarction, and neurodegenerative diseases.