TNP-470

• 产品号: T1455
• 分子式: C19H28ClNO6
• 分子量: 401.88172
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: TNP-470
• IUPAC标准名: (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl N-(2-chloroacetyl)carbamate
• IUPAC传统名: (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl N-(2-chloroacetyl)carbamate
• 别名: (Chloracetyl) carbamic acid (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]oct-6-yl ester; NSC 642492; O-Chloracetyl-carbamoyl fumagillol; AGM-1470

产品登记号

• MDL号: MFCD00870281

产品性质

• Empirical Formula (Hill Notation): C19H28ClNO6
• 纯度: ≥98% (HPLC)
• 外观: solid
• 溶解度: DMSO: >15 mg/mL
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• GHS警示性声明: P261
• 危险公开号: 36/37/38
• 安全公开号: 26
• 保存温度: -20°C
• 德国WGK号: 2

产品详细信息

详细说明 (English)

Other Notes
TNP-470 is hygroscopic.
Biochem/physiol Actions
TNP-470 is a methionine aminopeptidase-2 (MetAP-2) inhibitor, selective for MetAP-2 over MetAP11. TNP-470 is an antiangiogenic.

详细说明 (简体中文)

Other Notes
TNP-470 is hygroscopic.
Biochem/physiol Actions
TNP-470 is a methionine aminopeptidase-2 (MetAP-2) inhibitor, selective for MetAP-2 over MetAP11. TNP-470 is an antiangiogenic.