光辉霉素 A 来源于褶皱链霉菌

• 产品号: 69823
• CAS号: 18378-89-7
• 分子式: C52H76O24
• 分子量: 1085.14544
• 纯 度: ~80% (HPLC)

产品别名

• 标题: Mithramycin A from Streptomyces plicatus
• IUPAC标准名: (2S,3S)-3-[(1S,3S,4R)-3,4-dihydroxy-1-methoxy-2-oxopentyl]-2-{[(2S,4R,5R,6R)-4-{[(2S,4R,5R,6R)-4-{[(2S,4S,5R,6R)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy}-5-hydroxy-6-methyloxan-2-yl]oxy}-5-hydroxy-6-methyloxan-2-yl]oxy}-6-{[(2S,4R,5S,6R)-4-{[(2S,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy}-5-hydroxy-6-methyloxan-2-yl]oxy}-8,9-dihydroxy-7-methyl-1,2,3,4-tetrahydroanthracen-1-one
• IUPAC传统名: (2S,3S)-3-[(1S,3S,4R)-3,4-dihydroxy-1-methoxy-2-oxopentyl]-2-{[(2S,4R,5R,6R)-4-{[(2S,4R,5R,6R)-4-{[(2S,4S,5R,6R)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy}-5-hydroxy-6-methyloxan-2-yl]oxy}-5-hydroxy-6-methyloxan-2-yl]oxy}-6-{[(2S,4R,5S,6R)-4-{[(2S,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy}-5-hydroxy-6-methyloxan-2-yl]oxy}-8,9-dihydroxy-7-methyl-3,4-dihydro-2H-anthracen-1-one
• 别名: 普卡霉素; 金霉酸; Plicamycin; Aureolic acid

产品登记号

• PubChem SID: 24885983
• Beilstein号: 5236667
• CAS号: 18378-89-7
• MDL号: MFCD00135618

产品性质

• Empirical Formula (Hill Notation): C52H76O24
• 纯度: ~80% (HPLC)
• 适用性: suitable for fluorescence
• 荧光: λex 440 nm; λem 523 nm in 5 mM Tris; DNA
• GHS警示词: Warning
• GHS危险声明: H302
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• 危险公开号: 22
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Application
suitable for detection of DNA
Other Notes
Fluorescent stain for DNA in flow cytometry1,2
Biochem/physiol Actions
Anticancer antibiotic. Inhibits transcription and protein synthesis. Binds to DNA in native chromatin. Substrate of Pgp in MDR phenotypes.

详细说明 (简体中文)

Application
suitable for detection of DNA
Other Notes
Fluorescent stain for DNA in flow cytometry1,2
Biochem/physiol Actions
抗癌抗生素。抑制转录和蛋白质合成。与天然染色质中的 DNA 结合。MDR 表型的 Pgp 底物。