Concanamycin C from Streptomyces sp.

• 产品号: 27691
• CAS号: 81552-34-3
• 分子式: C45H74O13
• 分子量: 823.06126
• 纯 度: ~95% (HPLC)

产品别名

• 标题: Concanamycin C from Streptomyces sp.
• IUPAC标准名: (7R,8R,9S,10S,11R,17S,18R)-18-[(2S,3R,4S)-4-[(2R,4R,5S,6R)-4-{[(2R,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy}-2-hydroxy-5-methyl-6-(prop-1-en-1-yl)oxan-2-yl]-3-hydroxypentan-2-yl]-9-ethyl-8,10-dihydroxy-3,17-dimethoxy-5,7,11,13-tetramethyl-1-oxacyclooctadeca-3,5,13,15-tetraen-2-one
• IUPAC传统名: (7R,8R,9S,10S,11R,17S,18R)-18-[(2S,3R,4S)-4-[(2R,4R,5S,6R)-4-{[(2R,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy}-2-hydroxy-5-methyl-6-(prop-1-en-1-yl)oxan-2-yl]-3-hydroxypentan-2-yl]-9-ethyl-8,10-dihydroxy-3,17-dimethoxy-5,7,11,13-tetramethyl-1-oxacyclooctadeca-3,5,13,15-tetraen-2-one

产品登记号

• CAS号: 81552-34-3
• Beilstein号: 6628190
• MDL号: MFCD00216692

产品性质

• Empirical Formula (Hill Notation): C45H74O13
• 纯度: ~95% (HPLC)
• GHS警示词: Danger
• GHS危险声明: H300-H310-H319-H330
• 欧盟危险性物质标志: 剧毒(Highly toxic) (T+)
• 个人保护装置: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS警示性声明: P260-P264-P280-P284-P302 + P350-P305 + P351 + P338
• RID/ADR: UN 3462 6.1/PG 1
• 危险公开号: 26/27/28-36
• RTECS编号: GK6887000
• 安全公开号: 26-36/37/39-45
• 保存温度: -20°C
• 联合国危险货物等级: 6.1
• 联合国危险货物编号: 3462
• 联合国危险货物包装类别(PG): 1
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Application
Cancanamycin C, a vacuolar AT Pase, is used to suppress antigen presentation by MHC class II molecules. V-ATPases are responsible for the acidification of eukaryotic organelles such as endosomes and lysosomes and the vacuoles of plants and fungi 1
Biochem/physiol Actions
Concanamycin C inhibits v-ATPase (vacuolar-ATPase) and perturbs vacuolar organelle, endosome, and lysosome acidification processes. Used to suppress antigen presentation by MHC class II molecules.
Concanamycin C inhibits v-ATPase (vacuolar-ATPase) and perturbs vacuolar organelle, endosome, and lysosome acidification processes. Vacuolar ATPases, such as Concanamycin C, pump protons into the lumen of various endomembrane systems and cellular compartments 1.

详细说明 (简体中文)

Application
Cancanamycin C, a vacuolar AT Pase, is used to suppress antigen presentation by MHC class II molecules. V-ATPases are responsible for the acidification of eukaryotic organelles such as endosomes and lysosomes and the vacuoles of plants and fungi 1
Biochem/physiol Actions
Concanamycin C inhibits v-ATPase (vacuolar-ATPase) and perturbs vacuolar organelle, endosome, and lysosome acidification processes. Used to suppress antigen presentation by MHC class II molecules.
Concanamycin C inhibits v-ATPase (vacuolar-ATPase) and perturbs vacuolar organelle, endosome, and lysosome acidification processes. Vacuolar ATPases, such as Concanamycin C, pump protons into the lumen of various endomembrane systems and cellular compartments 1.