(+)-Fluprostenol

• 产品号: F4176
• 分子式: C23H29F3O6
• 分子量: 458.4679696
• 纯 度: ≥95%

产品别名

• 标题: (+)-Fluprostenol
• IUPAC标准名: 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl]cyclopentyl]hept-5-enoic acid
• IUPAC传统名: 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl]cyclopentyl]hept-5-enoic acid
• 别名: (+)-16-(m-Trifluoromethylphenoxy)tetranorprostaglandin F2α; (+)-9α,11α,15R-Trihydroxy-16-[3-(trifluoromethyl)phenoxy]-17,18,19,20-tetranorprosta-5Z,13E-dien-1-oic acid

产品登记号

• EC号: 200-578-6
• MDL号: MFCD00210955

产品性质

• abs.: ε/222 nm 9,700
• Empirical Formula (Hill Notation): C23H29F3O6
• 纯度: ≥95%
• 运输包装: wet ice
• 外观: ethanol solution
• 闪点: 14 °C
• 闪点: 57.2 °F
• GHS警示词: Danger
• GHS危险声明: H225
• 欧盟危险性物质标志: 易燃性(Flammable) (F)
• 个人保护装置: Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• GHS警示性声明: P210
• RID/ADR: UN 1170 3/PG 2
• 危险公开号: 11
• 安全公开号: 7-16
• 保存温度: -20°C
• 联合国危险货物等级: 3
• 联合国危险货物编号: 1170
• 联合国危险货物包装类别(PG): 2
• 德国WGK号: 2

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Metabolically stable analog of PGF2α ; potent FP prostanoid receptor agonist. The optically active enantiomer of fluprostenol. This product is expected to have twice the potency of (+/-)-fluprostenol. It inhibits PGF2α binding to human and rat FP receptors (IC50 values of 3.5 and 7.5 nM respectively). It is a more potent luteolytic agent than PGF2α in rat and also an inhibitor of rat adipose precursor differentiation in primary cultures (IC50 = 3 to 10 ×10-11 M).

详细说明 (简体中文)

Biochem/physiol Actions
Metabolically stable analog of PGF2α ; potent FP prostanoid receptor agonist. The optically active enantiomer of fluprostenol. This product is expected to have twice the potency of (+/-)-fluprostenol. It inhibits PGF2α binding to human and rat FP receptors (IC50 values of 3.5 and 7.5 nM respectively). It is a more potent luteolytic agent than PGF2α in rat and also an inhibitor of rat adipose precursor differentiation in primary cultures (IC50 = 3 to 10 ×10-11 M).