Dp44mT

• 产品号: SML0186
• CAS号: 152095-12-0
• 分子式: C14H15N5S
• 分子量: 285.3674
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Dp44mT
• IUPAC标准名: 1-{[bis(pyridin-2-yl)methylidene]amino}-3,3-dimethylthiourea
• IUPAC传统名: 1-{[bis(pyridin-2-yl)methylidene]amino}-3,3-dimethylthiourea
• 别名: Di-2-pyridylketone-4,4,-dimethyl-3-thiosemicarbazone; 2-(Di-2-pyridinylmethylene)-N,N-dimethyl-hydrazinecarbothioamide

产品登记号

• CAS号: 152095-12-0
• MDL号: MFCD20527329

产品性质

• Empirical Formula (Hill Notation): C14H15N5S
• 纯度: ≥98% (HPLC)
• 外观: yellow to orange powder
• 溶解度: DMSO: ≥5 mg/mL
• 保存温度: 2-8°C

产品详细信息

详细说明 (简体中文)

Caution
Material appears to be unstable in solution; make solutions immediately before use.
Biochem/physiol Actions
Dp44mT is an iron chelator that works as a selective anticancer agent. As other iron chelators it can serve as a therapeutic adjunct to doxorubicin treatment. Additionally Dm44mT possess DNA-damaging activity. It appears that that activity is mediated by top2a inhibition.