Tolcapone

• 产品号: SML0150
• CAS号: 134308-13-7
• 分子式: C14H11NO5
• 分子量: 273.24084
• 纯 度: ≥98% (HPLC)
• 保 存: desiccated

产品别名

• 标题: Tolcapone
• IUPAC标准名: 5-(4-methylbenzoyl)-3-nitrobenzene-1,2-diol
• IUPAC传统名: tolcapone (product)
• 别名: 3,4-Dihydroxy-4′-methyl-5-nitrobenzophenone; Ro 40-7592

产品登记号

• MDL号: MFCD00866569
• CAS号: 134308-13-7

产品性质

• Empirical Formula (Hill Notation): C14H11NO5
• 纯度: ≥98% (HPLC)
• 外观: yellow powder
• 溶解度: DMSO: ≥15 mg/mL
• 保存条件: desiccated
• 保存温度: 2-8°C

产品详细信息

详细说明 (简体中文)

Biochem/physiol Actions
Tolcapone is an orally active catechol-O-methyltransferase (COMT) inhibitor. It inhibits both central and peripheral COMT. Tolcapone crosses the blood-brain barrier, and has been used for L-DOPA adjunct therapy in the treatment of Parkinson′s Disease.