GLYX-13 trifluoroacetate

• 产品号: SML0109
• CAS号: 117928-94-6(freeacid)
• 分子式: C20H32F3N5O8
• 分子量: 527.4919896
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: GLYX-13 trifluoroacetate
• IUPAC标准名: (2S,3R)-2-{[(2S)-1-[(2S)-1-[(2S,3R)-2-amino-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]pyrrolidin-2-yl]formamido}-3-hydroxybutanamide; trifluoroacetic acid
• IUPAC传统名: (2S,3R)-2-{[(2S)-1-[(2S)-1-[(2S,3R)-2-amino-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]pyrrolidin-2-yl]formamido}-3-hydroxybutanamide; trifluoroacetic acid
• 别名: L-Threonyl-L-prolyl-L-prolyl-L-threoninamide trifluoroacetate; Thr-Pro-Pro-Thr-NH2 trifluoroacetate; TPPT-amide trifluoroacetate

产品登记号

• CAS号: 117928-94-6(freeacid)
• MDL号: MFCD20527320

产品性质

• Empirical Formula (Hill Notation): C18H31N5O6 · xC2HF3O2
• 纯度: ≥98% (HPLC)
• 运输包装: wet ice
• 外观: white to tan powder
• 保存温度: -20°C

产品详细信息

详细说明 (简体中文)

Biochem/physiol Actions
GLYX-13 is a glycine-site functional partial agonist (GFPA) selective modulator of the NMDA receptor (NMDAR). It is a brain penetrable tetrapeptide which acts as a positive allosteric modulator of the NMDA receptor, acting via the glycine site. GLYX-13 has been found to be a cognitive enhancer in learning models and is currently in clinical trials as an antidepressant.