SB 328437

• 产品号: SML0207
• CAS号: 247580-43-4
• 分子式: C21H18N2O5
• 分子量: 378.37802
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: SB 328437
• IUPAC标准名: methyl (2S)-2-(naphthalen-1-ylformamido)-3-(4-nitrophenyl)propanoate
• IUPAC传统名: methyl (2S)-2-(naphthalen-1-ylformamido)-3-(4-nitrophenyl)propanoate
• 别名: L-Phenylalanine, N-(1-naphthalenylcarbonyl)-4-nitro-, methyl ester

产品登记号

• CAS号: 247580-43-4
• MDL号: MFCD16618397

产品性质

• Empirical Formula (Hill Notation): C21H18N2O5
• 纯度: ≥98% (HPLC)
• 外观: white to tan powder
• 溶解度: DMSO: ≥10 mg/mL
• 保存温度: 2-8°C

产品详细信息

详细说明 (简体中文)

Biochem/physiol Actions
SB-328437 is a potent, selective CCR-3 antagonist (IC50 = 1.6 nM). The compound blockes CCR3 agonist-induced calcium mobilization in CCR3 expressing cells with the following IC50 values: eotaxin, 38 nM; eotaxin-2, 35 nM and MCP4, 20 nM.