dPPA

• 产品号: D7821
• CAS号: 54662-30-5
• 分子式: C30H36O7
• 分子量: 508.60264
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: dPPA
• IUPAC标准名: [(1R,2S,6R,10S,11R,13S,15R)-1,6-dihydroxy-4,12,12,15-tetramethyl-5-oxo-13-[(2-phenylacetyl)oxy]tetracyclo[8.5.0.0^2,^6.0^1^1,^1^3]pentadeca-3,8-dien-8-yl]methyl acetate
• IUPAC传统名: [(1R,2S,6R,10S,11R,13S,15R)-1,6-dihydroxy-4,12,12,15-tetramethyl-5-oxo-13-[(2-phenylacetyl)oxy]tetracyclo[8.5.0.0^2,^6.0^1^1,^1^3]pentadeca-3,8-dien-8-yl]methyl acetate
• 别名: 12-Deoxyphorbol 13-phenylacetate 20-acetate; DOPPA

产品登记号

• CAS号: 54662-30-5

产品性质

• Empirical Formula (Hill Notation): C30H36O7
• 纯度: ≥98% (HPLC)
• 外观: white to tan powder
• 溶解度: DMSO: ≥5 mg/mL
• 保存温度: -20°C

产品详细信息

详细说明 (简体中文)

Biochem/physiol Actions
Selective activator of PKC beta
dPPA is a phorbol ester that selectively activates the beta isotype of PKC. It is approximately 100-fold more potent for PKC-beta than the alpha, gamma or delta isotypes. PKC family members each have specific functions, but PKC-beta and delta appear to share similar expression profiles, and both are involved in regulating apoptosis and B cell activation, thus dPPA is a useful tool in determining PKCbeta specific signaling events.