Pemirolast potassium

• 产品号: SML0107
• CAS号: 100299-08-9
• 分子式: C10H7KN6O
• 分子量: 266.30048
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Pemirolast potassium
• IUPAC标准名: potassium 5-{9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}-1H-1,2,3,4-tetrazol-1-ide
• IUPAC传统名: potassium 5-{9-methyl-4-oxopyrido[1,2-a]pyrimidin-3-yl}-1H-1,2,3,4-tetrazol-1-ide
• 别名: 9-Methyl-3-(1H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one potassium salt; BMY 26517

产品登记号

• CAS号: 100299-08-9

产品性质

• Empirical Formula (Hill Notation): C10H7N6O·K
• 纯度: ≥98% (HPLC)
• 外观: light yellow to yellow with a green cast powder
• 溶解度: H2O: ≥18 mg/mL
• 保存温度: 2-8°C

产品详细信息

详细说明 (简体中文)

Biochem/physiol Actions
Pemirolast potassium is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent. It Inhibits chemical mediator release from tissue mast cells and has recently also been shown to inhibit the release of peptides including substance P, neurokinin (NK) A, and calcitonin gene-related peptide (CGRP) from sensory nerves. It has been used for the treatment of allergic conjunctivitis prophylaxis of for pulmonary hypersensitivity reactions to drugs such as paclitaxel