Tubacin

• 产品号: SML0065
• CAS号: 537049-40-4
• 分子式: C41H45N3O8S
• 分子量: 739.8763
• 纯 度: ≥98% (HPLC)
• 保 存: desiccated

产品别名

• 标题: Tubacin
• IUPAC标准名: N-{4-[(2R,4R,6S)-4-{[(diphenyl-1,3-oxazol-2-yl)sulfanyl]methyl}-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl}-N'-hydroxyoctanediamide hydrate
• IUPAC传统名: N-{4-[(2R,4R,6S)-4-{[(diphenyl-1,3-oxazol-2-yl)sulfanyl]methyl}-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl}-N'-hydroxyoctanediamide hydrate
• 别名: N1-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N8-hydroxy-octanediamide

产品登记号

• CAS号: 537049-40-4

产品性质

• Empirical Formula (Hill Notation): C41H43N3O7S
• 纯度: ≥98% (HPLC)
• 运输包装: wet ice
• 外观: white to tan powder
• 溶解度: DMSO: ≥10 mg/mL
• 保存条件: desiccated
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Tubacin is a selective inhibitor of histone deacetylase 6 (HDAC6), a predominantly cytoplasmic class II histone deacetylase that is involved in many cellular processes, including degradation of misfolded proteins, cell migration, and cell-cell interaction. Tubacin selectively inhibit HDAC6-mediated alpha -tubulin deacetylation.

详细说明 (简体中文)

Biochem/physiol Actions
Tubacin is a selective inhibitor of histone deacetylase 6 (HDAC6), a predominantly cytoplasmic class II histone deacetylase that is involved in many cellular processes, including degradation of misfolded proteins, cell migration, and cell-cell interaction. Tubacin selectively inhibit HDAC6-mediated alpha -tubulin deacetylation.