ZM 241385

• 产品号: Z0153
• CAS号: 139180-30-6
• 分子式: C16H15N7O2
• 分子量: 337.336
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: ZM 241385
• IUPAC标准名: 4-(2-{[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino}ethyl)phenol
• IUPAC传统名: 4-(2-{[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino}ethyl)phenol
• 别名: 4-(-2-[7-amino-2-{2-furyl}{1,2,4}triazolo{2,3-a} {1,3,5}triazin-5-yl-amino]ethyl)phenol

产品登记号

• CAS号: 139180-30-6
• MDL号: MFCD00908394

产品性质

• Empirical Formula (Hill Notation): C16H15N7O2
• 纯度: ≥98% (HPLC)
• 外观: white to tan powder
• 溶解度: DMSO: >15 mg/mL
• GHS警示词: Danger
• GHS危险声明: H301
• 欧盟危险性物质标志: 有毒(Toxic) (T)
• GHS警示性声明: P301 + P310
• 危险公开号: 25
• 安全公开号: 46
• 保存温度: room temp
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
ZM 241385 is a potent selective adenosine A2A antagonist. The A2A receptor plays a role in regulating myocardial oxygen consumption and coronary blood flow and is highly expressed in the brain, where it has important roles in the regulation of glutamate and dopamine release. ZM 241385 has neuroprotective effects and is being investigated for use in Parkinson′s and other neurodegenerative disorders.

详细说明 (简体中文)

Biochem/physiol Actions
ZM 241385 is a potent selective adenosine A2A antagonist. The A2A receptor plays a role in regulating myocardial oxygen consumption and coronary blood flow and is highly expressed in the brain, where it has important roles in the regulation of glutamate and dopamine release. ZM 241385 has neuroprotective effects and is being investigated for use in Parkinson′s and other neurodegenerative disorders.