D-Fructose 1,6-bisphosphate trisodium salt hydrate

• 产品号: F6803
• CAS号: 38099-82-0(anhydrous)
• 分子式: C6H13Na3O13P2
• 分子量: 424.076452
• 纯 度: ≥98% (TLC)

产品别名

• 标题: D-Fructose 1,6-bisphosphate trisodium salt hydrate
• IUPAC标准名: trisodium hydrate (3S,4R,5R)-3,4,5-trihydroxy-2-oxo-6-(phosphonatooxy)hexyl hydrogen phosphate
• IUPAC传统名: trisodium hydrate (3S,4R,5R)-3,4,5-trihydroxy-2-oxo-6-(phosphonatooxy)hexyl hydrogen phosphate
• 别名: Harden-Young ester; Hexose diphosphate trisodium salt hydrate; D(+)Fructofuranose 1,6-diphosphate trisodium salt hydrate

产品登记号

• CAS号: 38099-82-0(anhydrous)
• PubChem SID: 24894921
• MDL号: MFCD03427650

产品性质

• Empirical Formula (Hill Notation): C6H11Na3O12P2 · xH2O
• 纯度: ≥98% (TLC)
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Packaging
10 mg in autosample vial
Biochem/physiol Actions
Fructose-1,6-biphosphate (F1,6P) is a glycolytic intermediate produced by the transfer of a phosphate from ATP to fructose-6-phosphate by the enzyme phosphofructokinase. Fructose-1,6-biphosphate, along with fructose-2,6-biphosphate, modulates the activity of phosphofructokinase-1 (PFK-1), the rate-limiting step in glycolysis. During glycolysis, aldolase splits Fructose-1,6-biphosphate into dihydroxacetone phosphate (DHAP) and glyceraldehyde phosphate. Fructose-1,6-biphosphate is also an allosteric activator of the M2 isoform of Pyruvate Kinase (PK-M2), the predominant form of pyruvate kinase in cancer cells.

详细说明 (简体中文)

包装
10 mg in autosmp vl
Biochem/physiol Actions
Fructose-1,6-biphosphate (F1,6P) is a glycolytic intermediate produced by the transfer of a phosphate from ATP to fructose-6-phosphate by the enzyme phosphofructokinase. Fructose-1,6-biphosphate, along with fructose-2,6-biphosphate, modulates the activity of phosphofructokinase-1 (PFK-1), the rate-limiting step in glycolysis. During glycolysis, aldolase splits Fructose-1,6-biphosphate into dihydroxacetone phosphate (DHAP) and glyceraldehyde phosphate. Fructose-1,6-biphosphate is also an allosteric activator of the M2 isoform of Pyruvate Kinase (PK-M2), the predominant form of pyruvate kinase in cancer cells.