SD-169

• 产品号: S0572
• CAS号: 1670-87-7
• 分子式: C9H8N2O
• 分子量: 160.17262
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: SD-169
• IUPAC标准名: 1H-indole-5-carboxamide
• IUPAC传统名: indole-5-carboxamide
• 别名: indole-5-carboxamide

产品登记号

• PubChem SID: 24724600
• CAS号: 1670-87-7
• MDL号: MFCD07779486

产品性质

• Empirical Formula (Hill Notation): C9H8N2O
• 纯度: ≥98% (HPLC)
• 外观: white solid
• 溶解度: DMSO: ~18 mg/mL
• 溶解度: H2O: <2 mg/mL
• GHS警示词: Warning
• GHS危险声明: H302-H315-H319-H335
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 22-36/37/38
• 安全公开号: 26
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
SD-169 is an orally active, ATP-competitve, p38α-selective Mitogen-Activated Protein Kinase (MAPK) inhibitor. SD-169 demonstrates 38-fold potency against p38α MAP kinase (IC50 = 3.2 nM) than p38β MAP kinase (IC50 = 122 nM).

详细说明 (简体中文)

Biochem/physiol Actions
SD-169 is an orally active, ATP-competitve, p38α-selective Mitogen-Activated Protein Kinase (MAPK) inhibitor. SD-169 demonstrates 38-fold potency against p38α MAP kinase (IC50 = 3.2 nM) than p38β MAP kinase (IC50 = 122 nM).