JP-1302 三盐酸盐 水合物

• 产品号: J4899
• 分子式: C24H29Cl3N4O
• 分子量: 495.87226
• 纯 度: ≥98% (HPLC)
• 保 存: protect from light

产品别名

• 标题: JP-1302 trihydrochloride hydrate
• IUPAC标准名: N-[4-(4-methylpiperazin-1-yl)phenyl]acridin-9-amine hydrate trihydrochloride
• IUPAC传统名: N-[4-(4-methylpiperazin-1-yl)phenyl]acridin-9-amine hydrate trihydrochloride
• 别名: Acridin-9-yl-[4-(4-methylpiperazin-1-yl)-phenyl]amine 三盐酸盐 水合物; Acridin-9-yl-[4-(4-methylpiperazin-1-yl)-phenyl]amine trihydrochloride hydrate

产品登记号

• MDL号: MFCD11045293

产品性质

• Empirical Formula (Hill Notation): C24H27N4Cl3
• 纯度: ≥98% (HPLC)
• 外观: solid
• 溶解度: H2O: >10 mg/mL
• GHS警示词: Warning
• GHS危险声明: H302-H413
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• 危险公开号: 22
• 保存条件: protect from light
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
selective a2C-adrenoceptor antagonist displayed antagonism potencies KB of 1,500, 2,200 and 16 nM at the human a2A-, a2B-, and a2C-adrenoceptor subtypes, respectively; Ki = 28 nM; produced antidepressant and antipsychotic-like effects, i.e. it effectively reduced immobility in the forced specific antagonism of the a2C-adrenoceptor may have therapeutic potential as a novel mechanism for the treatment of neuropsychiatric disorders.

详细说明 (简体中文)

Biochem/physiol Actions
selective a2C-adrenoceptor antagonist displayed antagonism potencies KB of 1,500, 2,200 and 16 nM at the human a2A-, a2B-, and a2C-adrenoceptor subtypes, respectively; Ki = 28 nM; produced antidepressant and antipsychotic-like effects, i.e. it effectively reduced immobility in the forced specific antagonism of the a2C-adrenoceptor may have therapeutic potential as a novel mechanism for the treatment of neuropsychiatric disorders.