Imiquimod

• 产品号: I5159
• CAS号: 99011-02-6
• 分子式: C14H16N4
• 分子量: 240.30364
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Imiquimod
• IUPAC标准名: 1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine
• IUPAC传统名: imiquimod
• 别名: 1-(2-Methylpropyl)-1H-imidazole[4,5-c]quinoline-4-amine

产品登记号

• MDL号: MFCD00866946
• PubChem SID: 24724516
• CAS号: 99011-02-6

产品性质

• Empirical Formula (Hill Notation): C14H16N4
• 纯度: ≥98% (HPLC)
• 外观: solid
• 溶解度: H2O: <2 mg/mL
• 溶解度: DMSO: soluble4 mg/mL (warming to 60 °C for 15 minutes)
• GHS警示词: Danger
• GHS危险声明: H300-H315-H319-H335
• 欧盟危险性物质标志: 有毒(Toxic) (T)
• 个人保护装置: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS警示性声明: P261-P264-P301 + P310-P305 + P351 + P338
• RID/ADR: UN 2811 6.1/PG 3
• 危险公开号: 25-36/37/38
• 安全公开号: 26-45
• 联合国危险货物等级: 6.1
• 联合国危险货物编号: 2811
• 联合国危险货物包装类别(PG): 3
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Imiquimod is a caspase 3 activator, which directly induces procaspase 3 cleavage to active caspase 3. Imiquimod induces apoptosis in vivo in basal cell carcinoma. Its anti-tumor activity is related to the induction of apoptosis. Imiquimod has anti-angiogenic, anti-inflammatory, anti-viral activities. Imiquimod also acts as an immune response modulator inducing the secretion of various cytokines and chemokines.

详细说明 (简体中文)

Biochem/physiol Actions
Imiquimod is a caspase 3 activator, which directly induces procaspase 3 cleavage to active caspase 3. Imiquimod induces apoptosis in vivo in basal cell carcinoma. Its anti-tumor activity is related to the induction of apoptosis. Imiquimod has anti-angiogenic, anti-inflammatory, anti-viral activities. Imiquimod also acts as an immune response modulator inducing the secretion of various cytokines and chemokines.