AC-55649

• 产品号: A9480
• CAS号: 59662-49-6
• 分子式: C21H26O2
• 分子量: 310.42994
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: AC-55649
• IUPAC标准名: 4-(4-octylphenyl)benzoic acid
• IUPAC传统名: 4-(4-octylphenyl)benzoic acid
• 别名: 4′-Octyl-4-biphenylcarboxylic acid, 4′-n-octylbiphenyl-4-carboxylic acid; 8BCA

产品登记号

• PubChem SID: 24724405
• MDL号: MFCD00157040
• CAS号: 59662-49-6

产品性质

• Empirical Formula (Hill Notation): C21H26O2
• 纯度: ≥98% (HPLC)
• 相关基因信息: human ... RARB(5915)
• 外观: solid
• 溶解度: DMSO: >7 mg/mL
• GHS危险声明: H413
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
AC-55649 is a subtype selective RAR (RARβ2) agonist. AC-55649 is a potent, orally available isoform selective Retinoic Acid Receptor β2. AC-55649 has high selectivity, 99% for RARβ2 and 31% for RARβ1. When compared to the gold standard AM-580 (Cat. No A8843), both isoform receptors were 100%. AC-55649 has a potent EC50 of 6.9 μM compared to an EC50 of 7.7 μM for AM-580.

详细说明 (简体中文)

Biochem/physiol Actions
AC-55649 is a subtype selective RAR (RARβ2) agonist. AC-55649 is a potent, orally available isoform selective Retinoic Acid Receptor β2. AC-55649 has high selectivity, 99% for RARβ2 and 31% for RARβ1. When compared to the gold standard AM-580 (Cat. No A8843), both isoform receptors were 100%. AC-55649 has a potent EC50 of 6.9 μM compared to an EC50 of 7.7 μM for AM-580.