Biochem/physiol Actions 4-hydroxytamoxifen acid is a preferred tamoxifen analog, a nonsteroidal estrogenic compound for use in estrogen replacement therapy, and specifically menopause therapy. The estrogen replacements are administered to patients as the free acid or a pharmaceutically acceptable salt in combination with pharmaceutical carriers to alleviate conditions associated with a low level of estrogen, including osteoporosis, premenstrual syndrome, vasomotor symptoms associated with menopause, atrophic vaginitis, Kraurosis vulvae, female hypogonadism, primary ovarian failure, excessive hair growth and prostatic cancer. |
Biochem/physiol Actions 4-hydroxytamoxifen acid is a preferred tamoxifen analog, a nonsteroidal estrogenic compound for use in estrogen replacement therapy, and specifically menopause therapy. The estrogen replacements are administered to patients as the free acid or a pharmaceutically acceptable salt in combination with pharmaceutical carriers to alleviate conditions associated with a low level of estrogen, including osteoporosis, premenstrual syndrome, vasomotor symptoms associated with menopause, atrophic vaginitis, Kraurosis vulvae, female hypogonadism, primary ovarian failure, excessive hair growth and prostatic cancer. |