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(E/Z)-4-HTA monohydrate_分子结构_CAS_)
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(E/Z)-4-HTA monohydrate

产品号 H5039 公司名称 Sigma Aldrich
CAS号 公司网站 http://www.sigmaaldrich.com
分子式 C24H24O5 电 话 1-800-521-8956
分子量 392.44436 传 真
纯 度 ≥90% (HPLC) 电子邮件
保 存 Chembase数据库ID: 153113

产品价格信息

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产品别名

标题
(E/Z)-4-HTA monohydrate
IUPAC标准名
2-{4-[1-(4-hydroxyphenyl)-2-phenylbut-1-en-1-yl]phenoxy}acetic acid hydrate
IUPAC传统名
4-[1-(4-hydroxyphenyl)-2-phenylbut-1-en-1-yl]phenoxyacetic acid hydrate
别名
4-Hydroxytamoxifen acid
(E,Z)-2-[4-[1-(p-Hydroxyphenyl)-2-phenyl]-1-butenyl]phenoxyacetic acid

产品登记号

PubChem SID 24724502

产品性质

Empirical Formula (Hill Notation) C24H22O4 · H2O
纯度 ≥90% (HPLC)
外观 solid
溶解度 DMSO: >6 mg/mL
GHS危险品标识 GHS09
GHS警示词 Warning
GHS危险声明 H410
欧盟危险性物质标志 环境危害性(Nature polluting) 环境危害性(Nature polluting) (N)
MSDS下载 下载链接
个人保护装置 Eyeshields, Gloves
GHS警示性声明 P273-P501
RID/ADR UN 3077 9/PG 3
危险公开号 50/53
安全公开号 36/37-60-61
保存温度 2-8°C
联合国危险货物等级 9
联合国危险货物编号 3077
联合国危险货物包装类别(PG) 3
德国WGK号 3

产品详细信息

详细说明 (English)
Biochem/physiol Actions
4-hydroxytamoxifen acid is a preferred tamoxifen analog, a nonsteroidal estrogenic compound for use in estrogen replacement therapy, and specifically menopause therapy. The estrogen replacements are administered to patients as the free acid or a pharmaceutically acceptable salt in combination with pharmaceutical carriers to alleviate conditions associated with a low level of estrogen, including osteoporosis, premenstrual syndrome, vasomotor symptoms associated with menopause, atrophic vaginitis, Kraurosis vulvae, female hypogonadism, primary ovarian failure, excessive hair growth and prostatic cancer.
详细说明 (简体中文)
Biochem/physiol Actions
4-hydroxytamoxifen acid is a preferred tamoxifen analog, a nonsteroidal estrogenic compound for use in estrogen replacement therapy, and specifically menopause therapy. The estrogen replacements are administered to patients as the free acid or a pharmaceutically acceptable salt in combination with pharmaceutical carriers to alleviate conditions associated with a low level of estrogen, including osteoporosis, premenstrual syndrome, vasomotor symptoms associated with menopause, atrophic vaginitis, Kraurosis vulvae, female hypogonadism, primary ovarian failure, excessive hair growth and prostatic cancer.

参考文献