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Metharbital

产品号 DB00463 公司名称 DrugBank
CAS号 50-11-3 公司网站 http://www.ualberta.ca/
分子式 C9H14N2O3 电 话 (780) 492-3111
分子量 198.21906 传 真
纯 度 电子邮件 david.wishart@ualberta.ca
保 存 Chembase数据库ID: 346

产品价格信息

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产品别名

标题
Metharbital
IUPAC标准名
5,5-diethyl-1-methyl-1,3-diazinane-2,4,6-trione
IUPAC传统名
metharbital
商标名
Endiemal
Metabarbital
Methabarbitone
Methylbarbital
Endiemalum
Gemonal
Gemonil
Gemonit
Metarbital [INN-Spanish]
Metarbitale [Dcit]
Methabarbital
Metharbital [INN:Jan]
Metharbitalum [INN-Latin]
Metharbitone
Metharbutal
N-Methylbarbital

产品登记号

PubChem CID 4099
PubChem SID 46508167
CAS号 50-11-3

产品性质

疏水性(logP) 0.6
溶解度 1980 mg/L

产品详细信息

详细说明 (English)
Item Information
Drug Groups approved
Description Metharbital was patented in 1905 by Emil Fischer working for Merck. It was marketed as Gemonil by Abbott Laboratories. It is a barbiturate anticonvulsant, used in the treatment of epilepsy. It has similar properties to phenobarbital.

Indication Metharbital is used for the treatment of epilepsy.
Pharmacology Metharbital, a barbiturate, is used for the treatment of short term insomnia. It belongs to a group of medicines called central nervous system (CNS) depressants that induce drowsiness and relieve tension or nervousness. Little analgesia is conferred by barbiturates; their use in the presence of pain may result in excitation.
Toxicity Signs of overdose include confusion (severe), decrease in or loss of reflexes, drowsiness (severe), fever, irritability (continuing), low body temperature, poor judgment, shortness of breath or slow or troubled breathing, slow heartbeat, slurred speech, staggering, trouble in sleeping, unusual movements of the eyes, weakness (severe).
Affected Organisms
Humans and other mammals
External Links
Wikipedia

参考文献