苯并三氮唑-N,N,N′,N′-四甲基脲六氟磷酸酯

• 产品号: 12804
• CAS号: 94790-37-1
• 分子式: C11H16F6N5OP
• 分子量: 379.2418202
• 纯 度: ≥98.0% (T)

产品别名

• 标题: O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate
• IUPAC标准名: [(1H-1,2,3-benzotriazol-1-yloxy)(dimethylamino)methylidene]dimethylazanium; hexafluoro-λ^5-phosphanuide
• IUPAC传统名: [(1,2,3-benzotriazol-1-yloxy)(dimethylamino)methylidene]dimethylazanium hexafluorophosphate
• 别名: N,N,N′,N′-Tetramethyl-O-(1H-benzotriazol-1-yl)uronium hexafluorophosphate; HBTU; N,N,N′,N′-四甲基-O-(1H-苯并三氮唑)六氟磷酸脲

产品登记号

• Beilstein号: 7328329
• EC号: 423-020-5
• PubChem SID: 24847817
• CAS号: 94790-37-1
• MDL号: MFCD00075445

产品性质

• Empirical Formula (Hill Notation): C11H16F6N5OP
• 纯度: ≥98.0% (T)
• 熔点: 200 °C (dec.)(lit.)
• 溶解度: acetonitrile: soluble0.1 g/mL, clear
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 36/37/38
• 安全公开号: 26
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (简体中文)

Application
最近研究显示这种偶联试剂的晶体和溶液结构是胍的 N-氧化物形式，而不是一种脲化合物；1 用于肽合成的偶联剂；其优点在于：外消旋作用极低、反应条件简单、反应时间极短，以及极高的产率。2,3
包装
1, 5, 25 g in glass bottle

详细说明 (English)

Application
Recent studies show that crystal as well as solution structure of this coupling agent is a guanidinium N-oxide and not an uronium compound;1 Coupling reagent for peptide synthesis; advantages are: very low racemization, simple reaction conditions, very short reaction time, and high yields.2,3
Packaging
1, 5, 25 g in glass bottle