N,N-二甲基氯烯亚胺

• 产品号: 40766
• CAS号: 30354-18-8
• 分子式: C3H8ClN
• 分子量: 93.55532
• 纯 度: ≥95.0% (AT)

产品别名

• 标题: N,N-Dimethylmethyleneiminium chloride
• IUPAC标准名: dimethyl(methylidene)azanium chloride
• IUPAC传统名: dimethyl(methylidene)azanium chloride
• 别名: Eschenmoser 盐; Eschenmoser’s salt; Methylenedimethylammonium chloride; Dimethylformiminium chloride

产品登记号

• EC号: 250-142-4
• CAS号: 30354-18-8
• Beilstein号: 505955
• MDL号: MFCD00011809
• PubChem SID: 24865473

产品性质

• 线性分子式: CH2=N+(CH3)2Cl-
• 纯度: ≥95.0% (AT)
• 闪点: 82 °C
• 闪点: 179.6 °F
• 熔点: 146-148 °C(lit.)
• GHS警示词: Warning
• GHS危险声明: H228-H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P210-P261-P305 + P351 + P338
• RID/ADR: UN 1325 4.1/PG 3
• 危险公开号: 36/37/38
• 安全公开号: 26-36
• 联合国危险货物等级: 4.1
• 联合国危险货物编号: 1325
• 联合国危险货物包装类别(PG): 3
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Other Notes
"Mannich-reagent" for direct use; higher yields of purer products were achieved in shorter times compared with the classical "Mannich reaction"7,8,9; in-situ preparation of the reactive triflate with TMS-triflate10
Packaging
5, 25 g in glass bottle
Application
Reacant for:Preparation of dihydronaphthyridinones as HIV-1 integrase inhibitors1Mannich reactions2Preparation of cyanotetrahydrooxo-β-carbolines via cyclocondensation reactions3Asymmetric synthesis of phalarine via stereospecific Pictet-Spengler cyclocondensation and traceless chirality transfer from L-tryptophan4Synthesis of functionalized diarylpyrrolizines as inhibitors of microsomal prostaglandin E2 synthase-1 (mPGES-1) and 5-lipoxygenase (5-LOX)5Synthesis of (±)-phalarine with the rearrangement of an azaspiroindolenine and Gassman oxindole preparation as key steps6

详细说明 (简体中文)

Other Notes
供直接使用的"Mannich 试剂"；与传统的"Mannich 反应"相比，可在更短时间内生成产量和纯度更高的产物7,8,9；与三氟甲磺酸三甲基硅酯原位制备反应性三氟甲磺酸盐10
包装
5, 25 g in glass bottle
Application
Reacant for:Preparation of dihydronaphthyridinones as HIV-1 integrase inhibitors1Mannich reactions2Preparation of cyanotetrahydrooxo-β-carbolines via cyclocondensation reactions3Asymmetric synthesis of phalarine via stereospecific Pictet-Spengler cyclocondensation and traceless chirality transfer from L-tryptophan4Synthesis of functionalized diarylpyrrolizines as inhibitors of microsomal prostaglandin E2 synthase-1 (mPGES-1) and 5-lipoxygenase (5-LOX)5Synthesis of (±)-phalarine with the rearrangement of an azaspiroindolenine and Gassman oxindole preparation as key steps6